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substrate bikkam gingivali strain pesti culture activity cleavage speci anthraci table detection virulence d-amino acids presence speci ficity protease pestis strains infection enzyme d-amino plague spores microbiol disease yersinia study bikkam 1 substrate pneumonic plague porphyromonas gingivalis porphyromona ficity bacteria assay paper points animal netherland amsterdam result model point 37° c library anthracis spores paper bikkam substrates sample control periodontiti pathogen cleavage activity bikkam 14 sensitivity diagnosis peptide anthrax pneumonic 107 cfu /ml culture supernatants yersinia pestis wild-type gingipain pcd 1 plasmid gingivalis culture gingivalis substrates virulence genes plasmid l-bapna wild-type strains number enzyme activity cytokine 50 l hmsf – strains increase rf /min value subtilis kaman mouse model d-amino acid
3 Most Recent Publications
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Highly specific protease-based approach for detection of porphyromonas gingivalis in diagnosis of periodontitis
(Article)
Hays, J.P. Kaman, W.E. Galassi, F. Soet, J.J. de Bizzarro, S. Loos, B.G. Veerman, E.C.I. Belkum, A.F. van Bikkerk, F.J. |
2012-01-01
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Peptide-based fluorescence resonance energy transfer protease substrates for the detection and diagnosis of Bacillus species
(Article)
Kaman, W.E. Hulst, A.G. Alphen, P.T.W. van Roffel, S. Schans, M.J. van der Merkel, T. Belkum, A.F. van Bikker, F.J. |
2011-04-01
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A comprehensive study on the role of the Yersinia pestis virulence markers in an animal model of pneumonic plague
(Article)
Kaman, W.E. Hawkey, S. Kleij, D. van der Broekhuijsen, M.P. Silman, N.J. Bikker, F.J. |
2011-03-01
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