Vafadari, R.

patient tofacitinib transplantation t cells activation transplant blood effect tacrolimu pathway kidney study cytokine kidney transplant patients phosphorylation cytometry stat 5 phosphorylation inhibitor monitoring kinase phosphospecific flow cytometry analysis p-stat receptor chapter pharmacodynamic sample basiliximab recipient inhibition il -2 treatment phosphospecific pharmacodynamic monitoring rejection calcineurin level allograft bd biosciences kidney transplant recipients function organ p 38 mapk cd 4+ molecule /basiliximab concentration jak-stat transplant recipients response protein technique immunol result organ transplantation agent signal stat 5 activation therapy phase jak 3 control -15 ic 50 intracellular transcription efficacy target effector t cells immunosuppression figure phosphorylated expression factor development number kidney transplantation patients blood samples activity ënten