Bernatowska, E.

recombination patient recombination activity b-cell mutation precursor b-cell compartment activity rag genes rag-deficient scid patients rearrangement precursor rag 1 protein rag-deficient transfection compartment table precursor b cells differentiation bm samples children analysis scid patients blood arrest leukemia stage rag-scid non-t non-b scid cytometric sample rag 2 core domain scid -3 labeling ig loci b-cell differentiation arrest 820arg result detection wild-type rag genes lys 820arg mutation lymphocytes van dongen jjm disease composition control study lymphocyte immunoglobulin lymphocyte gate figure expression omenn syndrome b cells domain number rotterdam polymorphism mol cell biol rag 2 proteins rag 2 protein b-cell differentiation stages van gent dc codon flow cytometric analyses transfected kidney epithelial cells product level ig gene rearrangements absence rag 2 genes recombination activities gellert m rq-pcr erasmus mc rag mutations chromosome schatz dg