Bouma, G.

nod 2 function barrier tlr 2 epithelial epithelial cells cmt 93/69 cells barrier function expression stimulation 93/69 ligand response nlrp 3 disease immunology mdp prestimulation flammatory receptor claudin level epithelial barrier function prestimulation iec barrier function journal 2/tlr production chemokine monolayer flammatory bowel disease tlr 2/tlr heterodimers shrna mrna levels mrna expression crohn signi muramyl dipeptide cmt 93/69 monolayers tlr 2 responses claudin -3 junction effect protein ogura bacteria toll-like mdp pretreatment cxcl 1 domain pretreatment hiemstra cytokine layer mc 38 monolayers bowel 264–272 housekeeping genes cyclophilin recognition tlr 4 ligands fl uorescence microscopy pathway resistance cell –substrate impedance cario housekeeping gene cyclophilin dendritic cells cell survival inohara muramyl fluent monolayers science nunez non-targeting shrna nod 1 nature result signi ficantly factor chemistry mucus