Laine, L.

study patient therapy trial intervention endoscopic endoscopic therapy endoscopy analysis end point point ulcer study intervention criteria gastroenterology randomized difference population randomization result control outcome american journal investigator stigmata number blood assessment evidence lesion rebleeding panel factor hemoglobin american analyses journal review melena information nonvariceal index endoscopy hemorrhage management predefined practice group sample sample size randomized trials recommendation treatment methodology laine duration end points hemoglobin drop 7 days american college nonvariceal ugib baseline characteristics 30 days mortality presentation subgroup hematochezia astrazeneca method study groups revision example recording panel members characteristic hemodynamic instability table hypothesis reason schedule index