Vries, I.J.M. de

patient tumor mesothelioma response vaccination dendritic immunotherapy lysate dendritic cells study disease autologou tumor lysate cancer antigen autologous tumor cells chemotherapy table treatment figure blood injection vaccine increase activity serum survival dc immunotherapy trial tumor cells dendritic cell effect administration granzyme b expression assay granzyme dendritic cell vaccination autologous tumor lysate vries ij cytotoxicity punt cj fl uid antitumor netherland figdor cg ficient reaction 10 patients medicine release level therapy mesothelioma patients serum samples sample number antibody method result group immunol hegman tumor cell lysate 2- week intervals immunity department hypersensitivity tissue ct scans ctl activity fi rst vaccination m 2 macrophages system dc culture medium dif ficult keyhole limpet hemocyanin amount fi rst 50 3 106 hemocyanin