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b-cell patient 4*02 b cells memory b cells memory number ficiency cvid patients subset control pattern proliferation 6*02 3*02 4-34*01 3-23*01 t-cell immunol blood defect immunode b-cell subsets zone –like 3-22*01 immunode ficiency 1-26*01 –like recombination 6-13*01 5*02 figure level b-cell patterns erasmus mc replication 6-19*01 3-10*01 4-59*01 control subjects study analysis variant history subject 5 b-cell patterns atm kinase activity 3-21*01 group immunoglobulin signi result 6-1*01 b-cell proliferation center driessen 6*03 reduction antibody 5-18*01 repertoire ataxia telangiectasia signi ficantly division 3-7*01 table range allergy t cells b-cell compartment region 6-6*01 volume 4-17*01 age-matched controls fication 2-15*01 identi telangiectasia erasmu
2 Most Recent Publications
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Antibody deficiency in patients with ataxia telangiectasia is caused by disturbed B- and T-cell homeostasis and reduced immune repertoire diversity
(Article)
Driessen, G.J.A. IJspeert, H. Zelm, M.C. van Dongen, J.J.M. van Deuren, M. van Burger, C.W. Weemaes, C.M.R. Haraldsson, A. Trip, M. Warris, A. Flier, M. van der Wulffraat, N.M. Verhagen, M.M.M. Taylor, M.A. |
2013-04-08
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B-cell replication history and somatic hypermutation status identify distinct pathophysiologic backgrounds in common variable immunodeficiency
(Article)
Driessen, G.J.A. Zelm, M.C. van Dongen, J.J.M. van Burg, M. van der Hagen, P.M. van Hartwig, N.G. Trip, M. Warris, A. Vries, E. de Barendregt, B.H. Pico, I. Hop, W.C.J. |
2011-12-22
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