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scopus: 44761565600

Spek, A. van der

(Ashley van der Spek)


tcrgd t cells patient t-cell esrd patients figure population notch tcrgd þ cells differentiation control expression memory signi number rearrangement analysis pathway result cd thymocyte differentiation 0.001 percentage op 9-dl tcrab ficant apoptosi thymocyte leukemia dp cells disease receptor sample 0.01 signi ficantly table lineage immunol van coppernolle co-culture proliferation tcra rearrangements subset telomere article mgh betjes memory t cells phenotype kidney individual blood hemodialysi thymic mutation generation end-stage 0.0001 controls esrd patients mann – whitney t-cell subsets experiment tcrgd þ populations activation-induced apoptosis length 28null op 9-gfp telomere length trec content betje association difference tcrab þ cells von boehmer h cd 31 þ signi ficant differences 0.0001 p t-all presence dp pathway ficantly thymic output representative




2 Most Recent Publications

Notch induces human T-cell receptor γ δ+ thymocytes to differentiate along a parallel, highly proliferative and bipotent CD4 CD8 double-positive pathway (Article)
Coppernolle, S. van Vanhee, S. Plum, J. Langerak, A.W. Kerre, T. Vandekerckhove, B. Verstichel, G. Snauwaert, S. Spek, A. van der Velghe, I. Sinnesael, M. Heemskerk, M.H. Taghon, T. Leclercq, G.
2012-01-01
Premature aging of circulating T cells in patients with end-stage renal disease (Article)
Betjes, M.G.H. Langerak, A.W. Spek, A. van der Wit, E.A. de Litjens, N.H.R.
2011-07-02