Sigaux, F.

t-all mef 2c ptpn 2 expression figure cluster patient identi fied 2-1 ba /f cells identi lymphoblastic leukemia leukemia cancer nkx 2-1 control mutation oncogenic rearrangement jak 1 analysis protein sample lymphoblastic t-all cases level jak 1 mutations proliferative study blood oncogene t-cell mef 2c expression jak 1 mutants deletion factor table result transformation kinase inhibitor lmo 2 fusion transcription 2-5 sirna number knockdown 214-abl t cell development erasmus mc tyrosine subgroups shrna-control analyses chromosomal tlx 1-rearranged cases translocation ptpn 2 expression jak inhibitor i unsupervised shrna-ptpn lyl 1 method ptpn 2 inactivation nkx 2-1 rearrangements activation 2-2 april proliferation nkx 2-1/nkx elsevier fication ª2011 pathway nkx 2-5 soulier experiment growth sequence