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patient mutation cebpa leukemia aberration myeloid leukemia study myeloid group score children prognostic blood survival outcome treatment analysis pva score table figure factor cytogenetic result event trisomy karyotype childhood relapse type-i number oncology type-ii aberrations type-ii lymphoblastic leukemia coall cebpa mutations expression profile value trial type-i aberrations adult prognostic impact 3-itd zimmermann m therapy remission induction lymphoblastic frequency diagnosis double-mutant impact resistance event-free survival haematologica blood cell count cancer sensitivity cytogenetic aberrations promoter difference flt 3-itd npm 1 mutations hypermethylation level signi zwaan cm trisomy 19 correlation disease erasmus mc j clin oncol wt 1 mutations coall 06-97 study promoter hypermethylation gene expression profiles balgobind trisomy 8 adult aml
4 Most Recent Publications
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Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia
(Article)
Balgobind, B.V. Hollink, I.H.I.M. Zemanová, Z. Stary, J. Cayuela, J.M. Baruchel, A. Creutzig, U. Reinhardt, D. Pieters, R. Michel Zwaan, C. Heuvel-Eibrink, M.M. van den Arentsen-Peters, S.T.C.J.M. Zimmermann, M. Harbott, J. Beverloo, H.B. Bergh, A.R.M. von Cloos, J. Kaspers, G.J. Haas, V. de |
2011-10-01
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Prognostic significance of additional cytogenetic aberrations in 733 de novo pediatric 11q23/MLL-rearranged AML patients: Results of an international study
(Article)
Coenen, E.A. Raimondi, S. Hasle, H. Harrison, C.J. Heerema, N.A. Kaspers, G.J. Leszl, A. Litvinko, N. Nigro, L.L. Morimoto, A. Perot, C. Auvrignon, A. Harbott, J. Reinhardt, D. Rubnitz, J.E. Smith, F.O. Stary, J. Stasevich, I. Strehl, S. Taga, T. Tomizawa, D. Webb, D. Zemanová, Z. Zimmermann, M. Alonzo, T.A. Pieters, R. Zwaan, C.M. Heuvel-Eibrink, M.M. van den Beverloo, H.B. Chang, M. Creutzig, U. Dworzak, M.N. Forestier, E. Gibson, B. |
2011-06-30
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The long-term impact of in vitro drug sensitivity on risk stratification and treatment outcome in acute lymphoblastic leukemia of childhood (CoALL 06-97)
(Article)
Escherich, G. Tröger, A. Pieters, R. Boer, M.L. den Horstmann, M. Janka, G.E. Göbel, U. Graubner, U. Pekrun, A. Jorch, N. Kaspers, G.J.J.L. Zimmermann, M. Stadt, U.Z. Kazemier, K.M. |
2011-06-01
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Characterization of CEBPA mutations and promoter hypermethylation in pediatric acute myeloid leukemia
(Article)
Hollink, I.H.I.M. Heuvel-Eibrink, M.M. van den Trka, J. Baruchel, A. Creutzig, U. Pieters, R. Reinhardt, D. Zwaan, C.M. Arentsen-Peters, S.T.C.J.M. Zimmermann, M. Peeters, J. Valk, P.J.M. Balgobind, B.V. Sonneveld, E. Kaspers, G.J. Bont, E.S.J.M. de |
2011-03-01
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