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t-all c-myb expression figure analysis notch level genomic leukemia t-cell protein sample oncogenic blood cancer translocation lymphoblastic leukemia locus patient c-myb locus mutation transcript pathway lymphoblastic region number c-myb gene oncogene tcrb-myb activation c-myb expression mybdup myc protein levels leukemic france myc expression erasmus mc control mybdup cases notch 1 posttranscriptional volume panel rearrangement fication myc activation probe duplication abnormality identi identi fied breakpoint t-all samples notch 1 mutations chromosome target sequence subtype fbxw 7m genome transcription transcriptional 1/fbxw study group oncogenesi myc protein abundance adult myc expression levels dna copy gain array-cgh sil-tal database myc stabilization signi t-all cases chromosomal stabilization deregulation 6 tcrb-myb cases
2 Most Recent Publications
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Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia
(Article)
Bonnet, M. Loosveld, M. Mamessier, E. Roulland, S. Morgado, E. Formisano-Tréziny, C. Dik, W.A. Langerak, A.W. Prebet, T. Vey, N. Michel, G. Gabert, J. Montpellier, B. Soulier, J. Macintyre, E. Asnafi, V. Payet-Bornet, D. Nadel, B. Navarro, J.-M. Quilichini, B. Picard, C. Cristofaro, J.D. Bagnis, C. Fossat, C. Hernandez, L. |
2011-06-16
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The C-MYB locus is involved in chromosomal translocation and genomic duplications in human T-cell acute leukemia (T-ALL), the translocation defining a new T-ALL subtype in very young children
(Article)
Clappier, E. Cuccuini, W. Delattre, O. Aurias, A. Leblanc, T.M. Dombret, H. Gewirtz, A.M. Baruchel, A. Sigaux, F. Soulier, J. Kalota, A. Crinquette, A. Cayuela, J.-M. Dik, W.A. Langerak, A.W. Montpellier, B. Nadel, B. Walrafen, P. |
2007-08-15
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