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t-all expression figure protein notch level tlx 1 sample cancer leukemia ets 1 analysis oncogenic activation translocation rearrangement activity pathway control maturation transcriptional tlx 3 transcript mutation myc protein levels locus all-sil blood block lymphoblastic leukemia myc expression erasmus mc transcription tcrd-tlx 1 translocations t-cell tlx 1/tlx notch 1 vector posttranscriptional 1/tlx france genomic myc activation repression lymphoblastic receptor t-all samples result arrest fbxw 7m 1/fbxw development april segment oncogene tcrab myc protein abundance adult myc expression levels tcrd-tlx interaction patient element enhancer all-sil cells elsevier function ª2012 number ea activity myc stabilization sequence differentiation signi tlx-ets-mediated speci stabilization deregulation tlx à t-all tcrab expression
2 Most Recent Publications
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TLX Homeodomain Oncogenes Mediate T Cell Maturation Arrest in T-ALL via Interaction with ETS1 and Suppression of TCRα Gene Expression
(Article)
Dadi, S. Noir, S. le Radford, I. Verhoeyen, E. Cosset, F.L. Petit, A. Ifrah, N. Dombret, H. Hermine, O. Spicuglia, S. Langerak, A.W. Macintyre, E. Payet-Bornet, D. Nadel, B. Ferrier, P. Asnafi, V. Lhermitte, L. Zacarias-Cabeza, J. Bergeron-Sawitzke, J. Villarese, P. Vachez, E. Dik, W.A. Millien, C. |
2012-04-17
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Posttranscriptional deregulation of MYC via PTEN constitutes a major alternative pathway of MYC activation in T-cell acute lymphoblastic leukemia
(Article)
Bonnet, M. Loosveld, M. Mamessier, E. Roulland, S. Morgado, E. Formisano-Tréziny, C. Dik, W.A. Langerak, A.W. Prebet, T. Vey, N. Michel, G. Gabert, J. Montpellier, B. Soulier, J. Macintyre, E. Asnafi, V. Payet-Bornet, D. Nadel, B. Navarro, J.-M. Quilichini, B. Picard, C. Cristofaro, J.D. Bagnis, C. Fossat, C. Hernandez, L. |
2011-06-16
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