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study longevity association pathway analysis effect control leiden rs 2075650 rs 429358 replication leiden 85- disease rs gwas controls telomere cohort leiden longevity study protein netherland table survival lls gwas cases genet genome-wide population gwas data rotterdam study snp ratio test danish locus insulin apoe locus serum 85- nonagenarian level danish 1905 cohort deelen result christensen westendorp sample rotterdam allele snp analysis plink set-based test slagboom pe westendorp rg center leiden university van heemst slagboom iis pathway beekman research vaupel jw rs 7412 sibling phenotype cholesterol university parameter author family telomere length lls gwas signi tm pathways variant telomerase snp sets ª 2011 plink blauw gj pathway snp serum levels tm pathway craen aj 90 years beekman m
2 Most Recent Publications
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Gene set analysis of GWAS data for human longevity highlights the relevance of the insulin/IGF-1 signaling and telomere maintenance pathways
(Article)
Deelen, J. Uh, H.-W. Westendorp, R.G.J. Goeman, J.J. Slagboom, P.E. Houwing-Duistermaat, J.J. Beekman, M. Monajemi, R. Heemst, D. van Thijssen, P.E. Böhringer, S. Akker, E.B. van den de Craen, A.J.M. Rivadeneira Ramirez, F. Uitterlinden, A.G. |
2011-11-24
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Genome-wide association study identifies a single major locus contributing to survival into old age; the APOE locus revisited
(Article)
Deelen, J. Beekman, M. Akker, E.B. van den Passtoors, W.M. Tiemeier, H. Heemst, D. van de Craen, A.J.M. Rivadeneira Ramirez, F. Geus, E.J.C. de Perola, M. Ouderaa, F.J. van der Gunn, D.A. Uh, H.-W. Boomsma, D.I. Uitterlinden, A.G. Christensen, K. Tikka-Kleemola, P. Heijmans, B.T. Houwing-Duistermaat, J.J. Westendorp, R.G.J. Slagboom, P.E. Helmer, Q. Kuningas, M. Christiansen, L. Kremer, D. Breggen, R. van der Suchiman, H.E.D. Lakenberg, N. |
2011-08-01
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