Wolters, L.M.M.

patient lamivudine hepatitis therapy virus hepatitis b patients study group hepatitis b hepatitis b virus model lamivudine therapy entecavir nucleoside replication infection mutation polymerase analogue hbv dna level treatment decline effect baseline nucleoside analogues hepatocyte liver range chapter hepatitis b infection man ra assay combination serum phase month response resistance parameter hbeag famciclovir table hepatology result plasma detection withdrawal difference dynamic adefovir schalm sw agent cccdna concentration limit bi-phasic serum transaminases university hospital rotterdam lamivudinc activity schalm interferon co-infected barber j immunodeficiency virus efficacy emergence factor monotherapy inhibition tyrrell dl wolter honkoop p modeling thomas hc half-life immunodeficiency nucleoside analogue subject