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ttd mice wild-type wild-type mice periosteal apposition number bone strength volume decrease repair periosteal osteoblast difference apposition dna repair osteoclast strength formation thickness trabecular bone volume increase type mice 78 weeks culture 26 weeks 39 weeks analysis marrow study perimeter tibiae 13 weeks 52 weeks level damage transcription trichothiodystrophy parameter age-related endosteal animal differentiation oxidative stress femur stress syndrome adipocyte change mesenchymal bone mass endocortical volume genotype distribution apoptosi resorption bone formation factor thickness distribution mouse trabecular bone point ttd tibiae analyses bone marrow cultures phenotype dna damage endosteal bone formation bone resorption hoeijmaker model endocortical pth treatment tissue section surface expression bone nodule formation capacity treatment group
2 Most Recent Publications
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Bone fragility and decline in stem cells in prematurely aging DNA repair deficient trichothiodystrophy mice
(Article)
Diderich, K. Nicolaije, C. Hoeijmakers, J.H.J. Leeuwen, J.P.T.M. van Priemel, M. Waarsing, J.H. Day, J.S. Brandt, R.M.C. Schilling, A.F. Botter, S.M. Weinans, H.H. Horst, G.T.J. van der |
2012-08-01
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Age-related skeletal dynamics and decrease in bone strength in DNA repair deficient male trichothiodystrophy mice
(Article)
Nicolaije, C. Diderich, K. Horst, G.T.J. van der Hoeijmakers, J.H.J. Leeuwen, J.P.T.M. van Botter, S.M. Priemel, M. Waarsing, J.H. Day, J.S. Brandt, R.M.C. Schilling, A.F. Weinans, H.H. Eerden, B.C.J. van der |
2012-04-10
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