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expression pemetrexed nsclc i /11 cells sox 2 hmg 20b differentiation chd 7 knockdown cancer hrasl analysis erythroid protein hmg 20b knockdown gene expression tumor /11 figure erythroid differentiation study patient syndrome signature corest table microarray response group shrna control mouse target hrasls 3 factor binding level content tyms expression classi gfi 1b expression sensitivity marker fication erasmu pathway nsclc cell lines number subgroups therapy treatment transcription pemetrexed therapy target genes identi sox 2 peaks sample proerythroblast classi fication erasmus mc gfi 1b pemetrexed treatment charge syndrome globin neuroendocrine resistance hmg 20b depletion gfi 1b promoter pemetrexed response chromatin mutation staining cohort promoter charge repressor nature non-small chd 7 peaks volume
3 Most Recent Publications
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Expression profiling-based subtyping identifies novel non-small cell lung cancer subgroups and implicates putative resistance to pemetrexed therapy
(Article)
Hou, J. Lambers, M.E.H. Den Hamer, B. Bakker, M.A. den Hoogsteden, H.C. Grosveld, F.G. Hegmans, J.P. Aerts, J.G.J.V. Philipsen, S. |
2012-01-01
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The DNA binding factor Hmg20b is a repressor of erythroid differentiation
(Article)
Esteghamat, F. Dijk, T.B. van Horos, R. Pourfarzad, F. Lindern, M.M. von Philipsen, S. Braun, H. Dekker, S. Linden, R. van der Hou, J. Fanis, P. Demmers, J.A. IJcken, W.F.J. van Özgü, Z. |
2011-09-01
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Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes
(Article)
Engelen, E. Akinci, U. Demmers, J.A. Rijkers, E.J. Bhattacharya, S. Philipsen, S. Pevny, L.H. Grosveld, F.G. Rottier, R. Lenhard, B. Poot, R.A. Bryne, J.C. Hou, J. Gontan, C. Moen, M.H. Szumska, D. Kockx, C. IJcken, W.F.J. van Dekkers, D.H. |
2011-06-01
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