Bohnacker, T.

production pi 3k pathway il -1β production il -1β cytokine il -6 pi 3k triplicates ± sd proin flammatory cytokines pathway panel tnf -α activation response receptor result immunol stimulation wortmannin effect wt bmmcs flammatory p 110δ isoform proin ship 1−/− bmmcs costimulation experiment antigen hochd örfer lps-induced ligand secretion 20 min huber btk −/− bmmcs inhibitor lps-triggered isoform elisa triplicate germany c-kit krystal combination l 138.8a mcs p 110δ right panel point study p 110δd bmmcs factor l 138.8a bmmcs concentration amount differentially 138.8a bottom panel 866–875 örfer hochd regulation ly 294002 tnf -α secretion 1−/− −/− 100 nm wortmannin pi 3k isoform lps-triggered cytokine production bone marrow cells signi 110δd cytokine production ship 1 modulation igf -1. system lps stimulation constitutive activation right -33