Salonini, E.

airway patient group study treatment airways group dornase alfa fibrosis deposition dornase nebuliser airway deposition 4 weeks inhalation respir analysis adherence children difference aerosol per-protocol analysis function trial number change z-score particle expiratory flow lung function improvement intention-to-treat analysis maintenance treatment symptom disease volume inhalation technique device european expiratory per-protocol delivery fev 1 akita treatment groups particle size lung disease table treatment response inhaled cf patients score bakker randomised baseline value maintenance journal akita 2 journal e.m effect spirometry airway obstruction 2 weeks lung dose event intention-to-treat fibrosis patients technique response tidden material breathing nebulisation drug delivery jet nebuliser lung clearance index dornase alfa treatment lung deposition jet nebulisers symptom score