Koopman, M.

patient cancer colorectal treatment colorectal cancer metastatic colorectal cancer study oxaliplatin resection 5- fu /lv irinotecan survival metastatic trial chemotherapy regimen fluorouracil oncol capecitabine therapy stage folfox perspective colon cost-effectiveness erasmus mc resection resection hospital result raltitrexed bevacizumab leucovorin article tumour adjuvant netherland review adjuvant chemotherapy expert analysis pharmacother 5 fu /lv metastase erasmu schedule guideline first-line outcome surgery health disease phase mosaic trial practice month mosaic infusion combination quality 48 h infusion downloaded group cetuximab effect expert opin analyses cost-effectiveness ratio capox unresectable life year adjuvant treatment gramont liver fluoropyrimidine folfiri first-line treatment table 08/08/12 ef ficacy administration