Levi-Drummer, R.S.

patient interferon dose reduction group reduction decline change treatment effectiveness hepatitis c hepatitis parameter production slope phase phase slope virion production page number citation purposes study virion interferon effectiveness 3 mu interferon model interferon efficacy virus number induction group 2 effect 10 mu interferon efficacy gastroenterology kinetic 3 days group 2 patients interferon dose estimate response purpose result dynamic citation figure negativity table group 1 therapy 10 mu hcv rna negativity decrease ribavirin brouwer difference interferon dose reduction clearance bekkering genotype dose dependence 24 weeks induction dose schalm brouwer jt baseline sample 1.5 biphasic half-life neumann hepatology peginterferon alfa -2a interferon alfa hepatitis c virus clearance rate group 1 patients infection biphasic decline block 2 groups dependence