Fraser, F.

region expression effect element locus rearrangement level disease interaction chromatin development deletion factor position sox 9 study gene expression genome result sequence cd 2 lcr transcription protein change chromosomal genet hypersensitive resident gene example furrow number integration mammal globin press grosveld position effect breakpoint suppression nuclease-hypersensitive sites position effects el al resident control dna-binding proteins novel testis development domain boundaries host genome encode transcription factors heterochromatin boundary genomic frequency competition domain genomic rearrangements activation environment sex reversal shut-down schedl mm det ~tmallmtion milot rearrangement 88 kb proceedings t ?f myc expression 12. wt ~s bot target dna sequences mechanism mast-cell growth factor tyrosine kinase receptor sox 9 gene mgc-departme ~ff cell regulation position cuss pe t f m milot regio _rm tsanscrl ~ evidence