Witte-Bouma, J.

muc 2à/à mice expression muc 2þ/þ mice epithelial pathway analysis response transcription upregulated muc 2 coliti colon mucin table signi flammatory protein muc 2þ/þ number gene expression ficantly signi ficantly -02 cancer antimicrobial proteins extracellular development barrier receptor epithelial barrier function chemokine signi ficantly upregulated structure cytokine kegg pathway analysis october bowel change proliferation quanti fied ficiency junction j physiol volume qrt-pcr function downregulated factor cell growth process layer defense crypt epithelial proliferation upregulated genes colitis development muc 2à/à epithelial cells crypt lengths physiol microarray growth cmt -93 cells netherland muc 2à/à vs -03 length epithelial barrier dysfunction bacteria claudin speci murine flammatory response speci fically binding cell structure il -12 4 weeks level fically