Bhattacharya, S.

sox 2 chd 7 syndrome table binding knockdown expression sox 2 peaks charge syndrome mouse protein mutation factor target nature charge control chd 7 peaks cause development transcription immunoprecipitation regulation embryo input sox 2 binding defect gene regulation antibody genet genome otocyst genetic number target genes malformations right erasmus mc notch analysis genome-wide motif percentage sox 2+/− mice jag 1 expression chromatin anophthalmia 2+/− binding sites control chlp interaction experiment plane f-sox pathway microarray 7+/− netherland sequence erasmu wild-type analyses sequencing 2+chd america department genomic chd 7+/− mice twist sox 2 knockdown 2-chd alagille twist 1 f-sox 2 mrna levels image study sox 2+chd genes transcription factors e 12.5 embryos