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amyloid mutation patient app 692 mutation alzheimer disease plaque protein amyloid deposits dystrophic neurites amyloid core precursor deposit hemorrhage neurite brain dementia dystrophic vessel neuron lewy bodies amyloid precursor protein cortex hchwa-d antibody angiopathy codon presence family neuropathological broeckhoven change van duijnen sg martin martin jj layer neurofibrillary number haan j dutch abnormality nucleus filament chromosome examination tangle neuropathol phosphorylated capillarie report app 717 mutation diagnosis amyloid core sp mullan m vessel walls onset ad patients early-onset alzheimer masters cl chromosome 14- cerebellar cortex neurofibrillary tangles cerebellum amyloidosis-dutch type amyloidosi presenile app mutation app 693 mutation core amyloid plaques brain pathol 6 roques p vessel wall plaque size harskamp microglial cells patient iv -6 dutch type erasmus university acta neuropathol 84 missense mutation
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Presenile Alzheimer dementia characterized by amyloid angiopathy and large amyloid core type senile plaques in the APP 692 Ala => Gly mutation
(Article)
Cras, P. Harskamp, F. van Ceuterick, C. Duijn, C.M. van Stefanko, S.Z. Hofman, A. Kros, J.M. Broeckhoven, C. van Martin, J-J. Hendriks, L. |
1998-09-01
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