Vliet, M. van

tamoxifen patient cancer breast cyp 2c allele genotype cyp 2c allele study breast cancer patients cyp 2d tumor disease treatment cyp 2c carriers tamoxifen therapy cohort effect adjuvant cyp 2c genotype status breast cancer carrier cyp 2c activity breast cancer res therapy tamoxifen metabolism outcome cyp 2d genotype cyp 2c patients tamoxifen treatment metabolite group variant metabolism . clin figure breast tumor specimens month order endoxifen research result activity 4- oh-tamoxifen contact future -4-oh article @futuremedicine reprint survival estrogen science time-to-treatment failure netherland cyp 450 enzymes association pharmacogenomic disease-free hazard cancer res liver microsomes liver . natl time-to-treatment failure prognostic value noncarrier disease-free survival adjuvant tamoxifen factor prognostic pathway oh-tamoxifen receptor genotyping schaik cytochrome tamoxifen resistance