Berns, E.M.J.

cancer breast patient tamoxifen cohort breast cancer breast cancer patients allele 1100 delc cyp 2c genotype study family tumor carrier cyp 2c allele netherland control disease homozygote breast cancer risk variant status cyp 2d mutation breast cancer res frequency 1100 delc homozygotes lung cancer risk treatment cyp 2c carriers tamoxifen therapy genotyping effect adjuvant 1100 delc mutation cyp 2c genotype diagnosis cyp 2c activity origo cohort association therapy lung cancer tamoxifen metabolism 2*1100delc chek 2 contralateral breast cancer outcome netherlands pea huijts 1/2 cyp 2d genotype 1100 delc allele breast cancer cohort cyp 2c patients lung cancer cohort non-brca blood tamoxifen treatment metabolite group contralateral individual metabolism genetic number homozygosity origo . clin 1100 delc carriers figure allele frequency blood bank controls european journal breast cancer cases breast tumor specimens breast cancer patient fi ve patients genomic breast cancer diagnosis month