Breevaart Bravenboer, J. van de

cartilage alginate cell deformation deformation diameter chondrocyte interface compression study collagen strain articular wound treatment nucleus integration repair group articular cartilage tissue control value stress strength matrix sample 60 min period alginate concentration concentration collagen type iii change wound edges knight fibre approx nucleus deformation cell volume orthop y diameter strains enzyme-treated collagen type ii section articular cartilage repair ratio defect j bone volume / biochimica increase unstrained model behaviour morphology explant reduction enzyme-treated group interface area therapy vol 6 articular cartilage defects wound edge enzyme collagen type i signi £uence confocal agarose research technique surface nucleus morphology failure breevaart bravenboer cartilage repair hyaluronidase time points 25 min 5 weeks push-out diameter ratios ¢cant