Jong, A.P. de

protein pneumococcal pneumoniae variant strain streptococcus pneumoniae streptococcu sequence surface expression analysis serum opsonophagocytic activity phenotypic variants electrophoresis opsonophagocytic serotype immun proteinase maturation protein antibody pneumococcal strains virulence activity variation laboratory pneumococci infection bacteria maturation phenotypic blot analysis colony morphology buffer colony amount mass spectrometry proteinase rabbit vaccine ability peptide result number phenotype difference brile model phase tigr pneumococcal genome capsular pyruvate oxidase immunoelectron microscopy pneumococcal surface protein survival time ppma antibodies growth morphology surface-associated weiser study mcdaniel protection level pyruvate nasopharynx hyperimmune fraction protein electrophoresis preimmune serum oxidase pneumococcal proteins protein 3 production acid sequences phagocytosi nucleotide fluorescein isothiocyanate-labeled bacteria acid sequence analysis sds-polyacrylamide gel electrophoresis serum opsonophagocytic activity