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scopus: 6603826356

Diserens, A.C.

( A.C. Diserens)


glioblastoma methylation patient tumor cancer fication gefitinib model analysis sample treatment expression glioma status value survival classi trial study tissue probe classi fication promoter outcome mgmt methylation status pathway association gbm-o effect dataset methylated neuropathol mgmt methylation table grade mutation prediction mgmt promoter methylation phase oncol mgmt-stp prognostic factor group anaplastic oligodendroglioma-like component university bene fit month temozolomide -450k probability amplification mgmt-stp 27 methylation status hm -450k research identi receptor response 1.0 therapy feature 0.0 0.8 number component mgmt-stp 27 model information gefitinib treatment 0.6 0.4 van den mgmt promoter 0.2 department concentration lausanne island phospho-protein




3 Most Recent Publications

MGMT methylation analysis of glioblastoma on the Infinium methylation BeadChip identifies two distinct CpG regions associated with gene silencing and outcome, yielding a prediction model for comparisons across datasets, tumor grades, and CIMP-status (Article)
Bady, P. Sciuscio, D. Mcdonald, D.R. Lacombe, D. Stupp, R. Delorenzi, M. Hegi, M.E. Diserens, A.C. Bloch, J. Bent, M.J. van den Marosi, C. Dietrich, P-Y. Weller, M. Mariani, L. Heppner, F.L.
2012-10-01
Presence of an oligodendroglioma-like component in newly diagnosed glioblastoma identifies a pathogenetically heterogeneous subgroup and lacks prognostic value: central pathology review of the EORTC_26981/NCIC_CE.3 trial (Article)
Hegi, M.E. Janzer, R.C. Hamou, M.F. Bady, P. Weller, M. Bent, M.J. van den Mason, W.P. Mirimanoff, R.O. Stupp, R. Mokhtari, K. Wesseling, P. Lambiv, W.L. Gorlia, T. Kouwenhoven, M.C.M. Hartmann, C. Deimling, A. von Martinet, D. Besuchet Schmutz, N. Diserens, A.C.
2012-01-16
Pathway analysis of glioblastoma tissue after preoperative treatment with the EGFR tyrosine kinase inhibitor gefitinib - A phase II trial (Article)
Hegi, M.E. Diserens, A.C. Heppner, F. Yonekawa, Y. Merlo, A. Frei, K. Mariani, L. Hofer, S. Bady, P. Kamoshima, Y. Kouwenhoven, M.C.M. Delorenzi, M. Lambiv, W.L. Hamou, M.F. Matter, M.S. Koch, A.
2011-06-01