Wiekmeijer, A.-S.

mef 2c t-all cluster expression figure 2-1 identi fied nkx 2-1 patient identi rearrangement cancer sample proliferative lymphoblastic leukemia leukemia oncogene mef 2c expression t-all cases table oncogenic analysis lmo 2 control 2-5 lymphoblastic level t cell development subgroups translocation tlx 1-rearranged cases analyses chromosomal factor unsupervised study lyl 1 method nkx 2-1 rearrangements transcription 2-2 april fusion nkx 2-1/nkx elsevier fication ª2011 nkx 2-5 protein soulier probe development oncogenic rearrangements t-all subgroups nkx 2-1 fish unsupervised cluster analysis figure 1 c result ferrando proliferative cluster microarray target t-cell region loucy subtype vlierberghe blood van vlierberghe oncogenic hits t cell rotterdam notch 1-activating mutations breakpoint mef 2c levels tal /lmo subgroup sirna nkx 2-2 gene bone marrow controls rq-pcr