Sterenborg, H.J.

fluorescence measurement tissue wiley-vch verlag gmbh light patient tumor m-thpc center signal therapy treatment volume figure fiber mucosa blood variation photodynamic therapy vessel photosensitizer blood volume fraction university parameter system filter spectrum spectroscopy saturation cancer absorption spectra margin laser photobleaching m-thpc fluorescence wiley-vch study photodynamic biophotonic model monitoring weinheim illumination cavity effect netherlands cancer institute verlag reflectance treatment light representative article j component method vessel diameter oxygen sterenborg dc-fiber transmission probe tumor center amelink weinheim journal df signal volunteer photosensitizer concentration basis spectra wavelength difference technique m-thpc pdt fdps measurements photon excitation deviation photobiol concentration procedure setup microvascular oxygen saturation