Eringa, E.C.

artery model response control receptor group function study physiol diabetes dysfunction endothelin insulin microvascular microvascular dysfunction atherosclerosi signi ficantly conduit patient sfc ϩ dm porcine level development expression signi sturek m blood glucose vasoconstriction circulation vasodilation disease animal heart type 2 diabetes alteration sfc vs system control pigs l-name plasma mellitu p ϭ ns atherosclerosis development endothelium-dependent vasodilation liver vessel contribution ficantly result speci difference speci fic segment 10 wk study period tune jd complication artery function animal models ajp-heart www.ajpheart.org contrast van beusekom hm contractile hematoxylin eosin stain conduit arteries effect netherland artery disease dif ficult dm patients sfc pigs insulin resistance dick gm pharmacol concentration-dependent manner blockade sturek diabetes mellitus