Thiele, E.A.

patient epilepsy change tuberous sclerosis adaptive study outcome group signi iq /dq ficant mutation sclerosis seizure tuberou neurosurgery point seizure onset development epilepsy surgery behavior score surgery study group signi ficant decline history assessment scale intelligence number signi ficantly effect van eeghen interictal epileptiform discharges adaptive behavior npa 1 adaptive development analysis onset cohort discharge fi ndings autism neuropsychological assessment thiele ea quotient tsc 1 wechsler / epilepsy neuropsychological interval tsc 2 mutations children subgroup regression adaptive scores antiepileptic drugs variability nding result association interictal mutation type identi population trajectory table ficantly cognition thiele diagnosis fi rst npa observation center signi ficant difference fluence adaptive outcomes regression analysis characteristic