Rajsbaum, R.

mouse protein isg 15 conjugation herc 5 mherc isgylation mherc 6 herc 6 isg 15 mouse cells activity hherc conjugation plasmid mouse herc 6 virus sirna transfected hherc 6 ligase control l -929 cells expression domain herc proteins type i ifn transfection infection herc 5/6 proteins e 3 ligase hherc 5 hek -293t cells -929 assay luciferase target ifnb promoter mediate system issue localization january chimeric effect e 2 enzymes www.plosone.org volume function v 5-specific immunoblot reporter experiment type i interferon result -293t mouse isg 15 chimera sample promoter hela cells study hect domain sev infection rig-i level 5/6 enzyme target proteins conjugate interferon c-terminal hela cells transfected analysis induction firefly herc protein family 15. ifn induction figure isg 15 expression lanes mh 6