Audekerke, J. van

diffusion brain effect matter disease signi animal huntington ficant imaging study change tghd rat pups corpus callosum 0.001 cortex parameter development tissue kurtosi model callosum structure neuroimage tghd animals corpus postnatal section staining control value matter structures tensor hd rat pups level difference signi ficant differences signi ficant intensity blockx caudate putamen nmr biomed *mhtt signi ficantly signi ficant interaction diffusion tensor imaging striatum postnatal brain development region addition image capsule caudate table water cell death p 30. brain res rat brain fi ber bundles result myelin fi bers 2006. huntingtin system interaction 957–967 matrix tghd rats commissure rat model number analyses age *mhtt alteration dk parameters diffusivity analysis myelination