Kasteren, P.B. van

protein rig-i activity virus expression hek 293t cells domain dub activity response arteriviru ubiquitination infection protease encoding arteri 2-dub assay virol plasmid wild-type control addition activation result level nairoviru effect reporter residue ifn -␤ expression ubiquitin ifn -␤ response eav nsp 2-3 mda 5 ifn -␤ 2010. pathway transfected recognition overexpression 2-3 arteriviruse rlr pathway coronaviru interferon experiment erasmu eav rna cchfv downloaded library inhibition factor 2008. university virology jvi.asm.org chain irf 3 analysis transcription nairoviruse nairovirus dub-mediated replicase puri fied family nsp 2 polyprotein induction immunol virology downloaded rig-i ubiquitination snijder ej degradation evasion syndrome deubiquitinating number absence luciferase