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expression patient l-asp leukemia tel-aml lymphoblastic leukemia level aml 1 mrna expression group blood sample study lymphoblastic resistance childhood sensitivity l-asparaginase fusion 1-tel children leukemic aml 1 expression control asparagine cancer asparagine synthetase l-asp sensitivity prognosis synthetase expression levels value analysis tel-aml 1negative outcome pieters r bone marrow aml 1-tel mrna expression levels netherland tel-aml 1 mrna expression level 1negative tel-aml 1positive pieter difference prognostic nontranslocated tel allele aml 1-tel expression rotterdam marrow activity transcription erasmu leukemic cells probe deletion figure 1positive protein l-asp resistance oncology gapdh prednisolone allele microarray product translocation mechanism schuster sm tel allele drug resistance l-asp exposure exposure blood samples leukemia cell lines april vincristine erasmus mc /university life technologies
3 Most Recent Publications
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Expression levels of TEL, AML1, and the fusion products TEL-AML1 and AML1- TEL versus drug sensitivity and clinical outcome in t(12;21)-positive pediatric acute lymphoblastic leukemia.
(Article)
Stams, W.A. Boer, M.L. den Beverloo, H.B. Meijerink, J.P.P. Wering, E.R. van Janka-Schaub, G.E. Pieters, R. |
2005-04-15
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Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia
(Article)
Stams, W.A. Boer, M.L. den Holleman, A. Appel, I.M. Beverloo, H.B. Wering, E.R. van Janka-Schaub, G.E. Evans, W.E. Pieters, R. |
2005-01-01
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Sensitivity to L-asparaginase is not associated with expression levels of asparagine synthetase in t(12;21)+ pediatric ALL
(Article)
Stams, W.A. Boer, M.L. den Beverloo, H.B. Meijerink, J.P.P. Stigter, R.L. Wering, E.R. van Janka-Schaub, G.E. Slater, R. Pieters, R. |
2003-01-01
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