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patient expression leukemia lymphoblastic leukemia group lymphoblastic study children blood treatment infant analysis resistance childhood level sample fication sensitivity cancer value table relapse disease outcome drug resistance probe survival leukemic 75ntr ara-c apoptosi number receptor l-asp diagnosis blast prognostic protein result factor mrna expression protocol cd 40 expression figure subtype procaspase cohort p 75ntr caspase percentage leukemic cells concentration tel-aml coall netherland signi activation trial prognosis p 75ntr expression aml 1 response hospital apoptotic month pieter relapse-free survival parameter precursor gene-expression l-asparaginase marker lymphoblastic leukaemia range vincristine erasmu signi ficantly prednisolone assessment cd 40
10 Most Recent Publications
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Improved outcome with hematopoietic stem cell transplantation in a poor prognostic subgroup of infants with mixed-lineage-leukemia (MLL)-rearranged acute lymphoblastic leukemia: Results from the Interfant-99 Study
(Article)
Mann, G. Attarbaschi, A. Szczepański, T. Ferster, A. Janka-Schaub, G.E. Rubnitz, J.E. Silverman, L.B. Stary, J. Campbell, M. Li, C.K. Suppiah, R. Biondi, A. Schrappe, M. Vora, A. Valsecchi, M.G. Pieters, R. Lorenzo, P. de Peters, A.C.B. Hann, I. Rossi, G. de Felice, M. Lausen, B. Leblanc, T.M. |
2010-10-14
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Standardized MRD quantification in European all trials: Proceedings of the second international symposium on MRD assessment in Kiel, Germany, 18-20 September 2008
(Article)
Brüggemann, M. Schrauder, A. Biondi, A. Cavé, H. Dombret, H. Fielding, A.K. Foà, R. Gökbuget, N. Goldstone, A.H. Goulden, N. Henze, G. Hoelzer, D. Raff, T. Janka-Schaub, G.E. Macintyre, E. Pieters, R. Rambaldi, A. Ribera, J.M. Schmiegelow, K. Spinelli, O. Stary, J. Stackelberg, A. von Kneba, M. Pfeifer, H. Schrappe, M. Dongen, J.J.M. van Dworzak, M.N. Ottmann, O.G. Asnafi, V. Baruchel, A. Bassan, R. Benoit, Y. |
2010-03-01
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Pharmacokinetics of high-dose methotrexate in infants treated for acute lymphoblastic leukemia
(Article)
Lönnerholm, G. Valsecchi, M.G. Hann, I. Pieters, R. Lorenzo, P. de Schrappe, M. Hovi, L. Campbell, M. Mann, G. Janka-Schaub, G.E. Li, C.K. Stary, J. |
2009-05-01
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A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study
(Article)
Boer, M.L. den Slegtenhorst, M. van Horstmann, M.A. Janka-Schaub, G.E. Kamps, W.A. Evans, W.E. Pieters, R. Menezes, R.X. de Cheok, M.H. Buijs-Gladdines, J.G.C.A.M. Peters, S.T. Zutven, L.J.C.M. van Beverloo, H.B. Spek, P.J. van der Escherich, G. |
2009-02-01
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High expression of CD40 on B-cell precursor acute lymphoblastic leukemia blasts is an independent risk factor associated with improved survival and enhanced capacity to up-regulate the death receptor CD95
(Article)
Troeger, A. Glouchkova, L. Laws, H.J. Dilloo, D. Ackermann, B. Escherich, G. Meisel, R. Hanenberg, H. Boer, M.L. den Pieters, R. Janka-Schaub, G.E. Goebel, U. |
2008-08-15
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High nerve growth factor receptor (p75NTR) expression is a favourable prognostic factor in paediatric B cell precursor-acute lymphoblastic leukaemia
(Article)
Troeger, A. Gudowius, S. Willers, R. Harbott, J. Pieters, R. Goebel, U. Janka-Schaub, G.E. Hanenberg, H. Dilloo, D. Escherich, G. Boer, M.L. den Glouchkova, L. Ackermann, B. Meisel, R. Laws, H.J. Groeger, M. Wessalowski, R. |
2007-11-01
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Expression levels of TEL, AML1, and the fusion products TEL-AML1 and AML1- TEL versus drug sensitivity and clinical outcome in t(12;21)-positive pediatric acute lymphoblastic leukemia.
(Article)
Stams, W.A. Boer, M.L. den Beverloo, H.B. Meijerink, J.P.P. Wering, E.R. van Janka-Schaub, G.E. Pieters, R. |
2005-04-15
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Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia
(Article)
Stams, W.A. Boer, M.L. den Holleman, A. Appel, I.M. Beverloo, H.B. Wering, E.R. van Janka-Schaub, G.E. Evans, W.E. Pieters, R. |
2005-01-01
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Decreased PARP and procaspase-2 protein levels are associated with cellular drug resistance in childhood acute lymphoblastic leukemia
(Article)
Holleman, A. Boer, M.L. den Kazemier, K.M. Beverloo, H.B. Bergh, A.R.M. von Janka-Schaub, G.E. Pieters, R. |
2005-01-01
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Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment
(Article)
Holleman, A. Cheng, C. Veerman, A.J. Kazemier, K.M. Pei, D. Pui, C.H. Evans, W.E. Relling, M.V. Pieters, R. Janka-Schaub, G.E. Cheok, M.H. Boer, M.L. den Yang, W. |
2004-01-01
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