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patient resistance expression prednisolone leukemia lymphoblastic leukemia cancer subtype treatment group lymphoblastic probe 2- dg study glucose cohort value blood gene-expression glucocorticoid sensitivity childhood glucocorticoid resistance classi bcr –abl precursor bcr –abl disease analysis children precursor b-all cases b-all glycolysi probe sets coall survival bcr –abl cases gene expression fication tel-aml table number drug resistance vincristine prednisolone resistance classi fication copyright 2004 massachusetts pieters r leukemia cells daunorubicin disease outcome prognosis sample erasmu cell lines bcr –abl subtype netherland l-asp jurkat 6–runx pieter control level effect glucose consumption tel-aml 1negative figure b-other score pattern discovery asparaginase agent glycolytic gene-expression patterns microarray gene-probe sets antileukemic agents www.nejm.org erasmus mc
5 Most Recent Publications
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Inhibition of glycolysis modulates prednisolone resistance in acute lymphoblastic leukemia cells
(Article)
Hulleman, E. Kazemier, K.M. Holleman, A. VanderWeele, D.J. Rudin, C.M. Broekhuis, M.J.C. Evans, W.E. Pieters, R. Boer, M.L.D. |
2009-02-26
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A subtype of childhood acute lymphoblastic leukaemia with poor treatment outcome: a genome-wide classification study
(Article)
Boer, M.L. den Slegtenhorst, M. van Horstmann, M.A. Janka-Schaub, G.E. Kamps, W.A. Evans, W.E. Pieters, R. Menezes, R.X. de Cheok, M.H. Buijs-Gladdines, J.G.C.A.M. Peters, S.T. Zutven, L.J.C.M. van Beverloo, H.B. Spek, P.J. van der Escherich, G. |
2009-02-01
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The SWI/SNF chromatin-remodeling complex and glucocorticoid resistance in acute lymphoblastic leukemia
(Article)
Pottier, N. Yang, W. Evans, W.E. Cheok, M.H. Assem, M. Panetta, J.C. Pei, D. Paugh, S.W. Cheng, K.L. Boer, M.L. den Relling, M.V. Pieters, R. |
2008-12-17
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Asparagine synthetase expression is linked with L-asparaginase resistance in TEL-AML1-negative but not TEL-AML1-positive pediatric acute lymphoblastic leukemia
(Article)
Stams, W.A. Boer, M.L. den Holleman, A. Appel, I.M. Beverloo, H.B. Wering, E.R. van Janka-Schaub, G.E. Evans, W.E. Pieters, R. |
2005-01-01
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Gene-expression patterns in drug-resistant acute lymphoblastic leukemia cells and response to treatment
(Article)
Holleman, A. Cheng, C. Veerman, A.J. Kazemier, K.M. Pei, D. Pui, C.H. Evans, W.E. Relling, M.V. Pieters, R. Janka-Schaub, G.E. Cheok, M.H. Boer, M.L. den Yang, W. |
2004-01-01
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