Hagerman, P.J.

inclusion protein neuron sam 68 level cgg aggregates brain mouse hagerman aggregate precgg figure patient premutation syndrome fxtas patients intranuclear intranuclear inclusions model genet carrier tremor tassone fmr 1 mrna culture antibody fmr 1 gene cos 7 cells expression analysis control precgg neurons mouse model cgg mice /ataxia mbnl 1 study x syndrome result gland number transfection pm carriers erasmus university rotterdam ubiquitin-positive formation hippocampal expanded-repeat ubiquitin-positive intranuclear inclusions 60 cgg corticosterone wt mice corticosterone levels signi disease littermate alternative dendritic hnrnp-g willemsen presence tautomycin sam 68 protein 21 div genetic plasmid expansion regulation premutation carriers length 2010 european symptom hippocampal neurons expanded-repeat mice wt littermates allele nuclei amygdala cgg rna aggregates transfected