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airway dendritic t cells cytokine response flammation number expression immunol level asthma 2 cells bal fl uid model group dendritic cells ova-dc airway inflammation production -12 ligand allograft chemokine control effect aerosol antibody development transplantation t 1/st il -4 challenge injection inflammation receptor il -12 production mouse experiment lps stimulation flt 3l fl ow cytometry tracheal increase goblet cell hyperplasia il -12 stimulation figure treatment molecule patient trachea secretion lymphocytes 2 responses ova aerosols epithelial cells mhcii allergen plasmacytoid flt 3l treatment cd 28/ mice syngraft exposure ovalps-dc antigen ccr 4 epithelial sensitization flammatory intratracheal injection staining study plasmacytoid dendritic cells ccr 4 ligands activation mouse model il -12p allergen challenge airway eosinophilia tarc /ccl
5 Most Recent Publications
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An anti-inflammatory role for plasmacytoid dendritic cells in allergic airway inflammation
(Article)
Kool, M. Nimwegen, M. van Hammad, H. Willart, M.A. Muskens, F. Boon, L. Smit, J.J. Coyle, A.J. Clausen, B.E. Hoogsteden, H.C. Lambrecht, B.N.M. |
2009-07-15
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Blockade of CCR4 in a humanized model of asthma reveals a critical role for DC-derived CCL17 and CCL22 in attracting Th2 cells and inducing airway inflammation
(Article)
Perros, F. Hoogsteden, H.C. Coyle, A.J. Lambrecht, B.N.M. Hammad, H. |
2009-07-01
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Inducible costimulator blockade prolongs airway luminal patency in a mouse model of obliterative bronchiolitis
(Article)
Kleinjan, A. Willart, M.A. Kuipers, H. Coyle, A.J. Hoogsteden, H.C. Lambrecht, B.N.M. |
2008-11-27
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Lipopolysaccharide-induced suppression of airway Th2 responses does not require IL-12 production by dendritic cells
(Article)
Kuipers, H. Hijdra, D. Vries, V.C. de Hammad, H. Prins, J-B. Coyle, A.J. Hoogsteden, H.C. Lambrecht, B.N.M. |
2003-01-01
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Myeloid dendritic cells induce Th2 responses to inhaled antigen, leading to eosinophilic airway inflammation
(Article)
Lambrecht, B.N.M. Veerman, M. de Coyle, A.J. Gutierrez-Ramos, J.C. Thielemans, K. Pauwels, R.A. |
2000-01-01
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