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globin locus expression b-globin 59 hs 5 promoter globin genes region analysis sequence protein level transcription probe motif binding result control b-globin gene erythroid cells figure hypoxia mouse element deletion globin gene transgene globin loci erythroid assay reaction pufferfish effect globin locus activity chromosome fragment position beas -2b cells hela cells b-globin locus study factor hypersensitive genome b-globin gene expression cosmid cytoglobin primers number chromatin sh-sy 5y cells beas -2b grosveld primer structure sh-sy table 3 c analysis patient promoter activity antibody hemoglobin hong kong beta-globin binding af finity figuration 16orf neuroglobin ngb promoter blood hre motifs hybridization hif -1a normoxia regulation oligonucleotide globin gene expression 3 c experiments university
6 Most Recent Publications
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Functional and sequence analysis of human neuroglobin gene promoter region
(Article)
Zhang, W.Y. Tian, Z. Sha, S. Cheng, L.Y.L. Philipsen, S. Tan-Un, K. |
2011-04-01
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5′ HS5 of the Human β-globin Locus Control Region is dispensable for the formation of the β-globin active chromatin hub
(Article)
Chan, P.K. Wai, A. Philipsen, S. Tan-Un, K. |
2008-05-07
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Study of the hypoxia-dependent regulation of human CYGB gene
(Article)
Guo, X. Philipsen, S. Tan-Un, K. |
2007-12-07
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The study of sequence configuration and functional impact of the (AC) n(AT)xTy motif in human β-globin gene promoter
(Article)
Chan, P.K. Ma, E.S.K. Philipsen, S. Tan-Un, K. |
2007-05-01
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Functional and comparative analysis of globin loci in pufferfish and humans
(Article)
Gillemans, N. Tan-Un, K. Langeveld, A. Higgs, D. Philipsen, J.N.J. Grosveld, F.G. McMorrow, T. Tewari, R. Wai, A.W. Burgtorf, C. Drabek, D.D. Ventress, N. |
2003-01-01
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The dynamics of gene expression: frequency and duration of transcription.
(Article)
Milot, E. Strouboulis, J. Fraser, P. Trimborn, T. Wijgerde, M.G.J.M. Boer, E. de Langeveld, A. Tan-Un, K. Vergeer, W. Yannoutsos, N. Grosveld, F.G. |
1996-10-01
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