London, M.J.

patient surgery perioperative blocker heart noncardiac surgery trial study ␤- blockers effect heart rate therapy ␤- blocker therapy ischemic threshold ischemia noncardiac placebo mortality heart rate control netherland ischemic randomized result beta-blocker research threshold incidence perioperative beta-blocker therapy ␤- blocker use metoprolol troponin t release plaque rupture heart rates polderman bax jj postoperative atenolol antiinflammatory effects boersma e plaque evidence outcome morbidity complication event research grant perioperative beta-blockade stress response dose titrated infarction anesthesia blood pressure risk evaluation non-cardiac surgery surgery patients perioperative mi postoperative ischemia holter monitoring dutch echocardiographic population thrombus formation pobble in-hospital mortality randomized trials schouten mangano benefit oxygen beta-blocker therapy oxygen demand department group boersma dipom perioperative beta-blocker trials leven ” foundation ␤- blocker perioperatively preoperative dobutamine stress-echocardiography patients heart rate