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10 Most Recent Publications
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Low-density lipoprotein receptor mutations generate synthetic genome-wide associations
(Article)
Oosterveer, D.M. Versmissen, J. Kastelein, J.J.P. Aulchenko, Y.S. Sijbrands, E.J.G. Defesche, J.C. Sivapalaratnam, S. Yazdanpanah, M. Mulder, M. Zee, L. van der Uitterlinden, A.G. Tikka-Kleemola, P. Hofman, A. |
2012-09-12
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A frequent variant in the ABCA1 gene is associated with increased coronary heart disease risk and a better response to statin treatment in familial hypercholesterolemia patients
(Article)
Versmissen, J. Oosterveer, D.M. Yazdanpanah, M. Mulder, M. Dehghan, A. Defesche, J.C. Kastelein, J.J. Sijbrands, E.J.G. |
2011-02-01
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Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease
(Article)
Schunkert, H. König, I.R. Absher, D. Peters, A. Peyvandi, F. Qu, L. Quyyumi, A.A. Rader, D.J. Rallidis, L.S. Rice, C. Rosendaal, F.R. Rubin, D. Salomaa, V. Aherrahrou, Z. Sampietro, M.L. Sandhu, M.S. Schadt, E.E. Scḧsignfer, A. Schillert, A. Schreiber, S. Schrezenmeir, J. Schwartz, S.M. Siscovick, D.S. Sivananthan, M. Allayee, H. Sivapalaratnam, S. Smith, A.V. Snoep, J.D. Soranzo, N. Spertus, J.A. Stark, K. Stirrups, K. Stoll, M. Tang, W.H.W. Tennstedt, S. Altshuler, D. Thorgeirsson, G. Thorleifsson, G. Tomaszewski, M. Uitterlinden, A.G. Rij, A.M. van Voight, B.F. Wareham, N.J. Wells, G. Wichmann, H.E. Wild, P.S. Anand, S.S. Willenborg, C. Witteman, J.C.M. Wright, B.J. Ye, S. Zeller, T. Ziegler, A. Cambien, F. Goodall, A.H. Cupples, L.A. Quertermous, T. Andersen, K. Mäsignrz, W. Hengstenberg, C. Blankenberg, S. Ouwehand, W.H. Hall, A.S. Kastelein, J.J.P. Deloukas, P. Thompson, J.R. Stefansson, K. Roberts, R. Anderson, J.L. Thorsteinsdottir, U. O'Donnell, C.J. McPherson, R. Erdmann, J. Samani, N.J. Ardissino, D. Ball, S.G. Balmforth, A.J. Kathiresan, S. Barnes, T.A. Becker, D.M. Berger, K. Bis, J.C. Boekholdt, S.M. Boerwinkle, E. Braund, P.S. Brown, M.J. Burnett, M.S. Buysschaert, I. Reilly, M.P. Carlquist, J.F. Chen, L. Cichon, S. Codd, V. Davies, R.W. Dedoussis, G.V. Dehghan, A. Demissie, S Devaney, J. Diemert, P. Assimes, T.L. Do, R. Doering, A. Eifert, S. Mokhtari, N.E.E. Ellis, S.G. Elosua, R. Engert, J.C. Epstein, S.E. Faire, U. de Fischer, M. Holm, H. Folsom, A.R. Freyer, J. Gigante, B. Girelli, D. Gretarsdottir, S. Gudnason, V. Gulcher, J.R. Halperin, E. Hammond, N. Hazen, S.L. Preuss, M. Hofman, A. Horne, B.D. Illig, T. Iribarren, C. Jones, G.T. Jukema, J.W. Kaiser, M.A. Kaplan, R. Khaw, K-T. Knowles, J.W. Stewart, A.F.R. Kolovou, G. Kong, A. Laaksonen, R. Lambrechts, D. Leander, K. Lettre, G. Li, X. Lieb, W. Loley, C. Lotery, A.J. Barbalic, M. Mannucci, P.M. Maouche, S. Martinelli, N. McKeown, P.P. Meisinger, C. Meitinger, T. Melander, O. Merlini, P.A. Mooser, V. Morgan, T. Gieger, C. Mühleisen, T.W. Muhlestein, J.B. Münzel, T. Musunuru, K. Nahrstaedt, J. Nelson, C.P. Nöthen, M.M. Olivieri, O. Patel, R.S. Patterson, C.C. |
2011-02-01
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Biological, clinical and population relevance of 95 loci for blood lipids
(Article)
Teslovich, T.M. Musunuru, K. Johansen, C.T. Marroni, F. Mangino, M. Magnusson, P.K. Lucas, G. Luben, R.N. Loos, R.J.F. Lokki, M.L. Lettre, G. Langenberg, C. Launer, L.J. Fouchier, S.W. Lakatta, E. Laaksonen, R. Kyvik, K.O. Kronenberg, F. König, I.R. Khaw, K-T. Kaprio, J. Kaplan, R. Johansson, Å. Jarvelin, M.R. Isaacs, A. Cecile, A. Ingelsson, E. Igl, W. Kees Hovingh, G. Hottenga, J.J. Hofman, A. Hicks, A.A. Hengstenberg, C. Heid, I.M. Hayward, C. Peloso, G.M. Havulinna, A.S. Hastie, N. Harris, T.B. Haritunians, T. Hall, A.S. Gyllensten, U. Guiducci, C. Groop, L. Gonzalez, E. Gieger, C. Barbalic, M. Freimer, N.B. Ferrucci, L. Erdmann, J. Elliott, P. Ejebe, K.G. Döring, A. Dominiczak, A. Demissie, S Deloukas, P. Geus, E.J.C. de Ricketts, S.L. Faire, U. de Crawford, G. Collins, F.S. Chen, C. Caulfield, M. Campbell, H. Burtt, N.P. Bonnycastle, L.L. Boomsma, D.I. Boekholdt, S.M. Bis, J.C. Bergman, R.N. Barroso, I. Bandinelli, S. Ballantyne, C. Assimes, T.L. Quertermous, T. Altshuler, D. Seielstad, M. Wong, T.Y. Tai, E.S. Aulchenko, Y.S. Feranil, A.B. Kuzawa, C.W. Adair, L.S. Taylor, H.A. Borecki, I.B. Gabriel, S.B. Holm, H. Thorsteinsdottir, U. Gudnason, V. Krauss, R.M. Thorleifsson, G. Mohlke, K.L. Ordovas, J.M. Munroe, P. Kooner, J.S. Tall, A.R. Hegele, R.A. Kastelein, J.J. Schadt, E.E. Rotter, J.I. Boerwinkle, E. Feitosa, M.F. Strachan, D.P. Mooser, V. Zwart, J-A. Reilly, M.P. Samani, N.J. Schunkert, H. Cupples, L.A. Sandhu, M.S. Ridker, P.M. Rader, D.J. Smith, A.V. Chambers, J. Tikka-Kleemola, P. Peltonen, L. Abecasis, G.R. Boehnke, M. Kathiresan, S. O'Donnell, C.J. Orho-Melander, M. Melander, O. Johnson, T. Li, X. Guo, X. Shin Cho, Y. Jin Go, M. Jin Kim, Y. Lee, J.Y. Edmondson, A.C. Park, T. Kim, K. Sim, X. Twee-Hee Ong, R. Croteau-Chonka, D.C. Lange, L.A. Song, K. Hua Zhao, J. Yuan, X. Luan, J. Stylianou, I.M. Lamina, C. Ziegler, A. Zhang, W. Zee, R.Y.L. Wright, A.F. Witteman, J.C.M. Wilson, J.F. Willemsen, G.A.H.M. Wichmann, H.E. Whitfield, J. Koseki, M. Waterworth, D. Wareham, N.J. Waeber, G. Vollenweider, P. Voight, B.F. Vitart, V. Uitterlinden, A.G. Uda, M. Tuomilehto, J. Thompson, J.R. Pirruccello, J.P. Tanaka, T. Surakka, I. Stringham, H.M. Spector, T.D. Soranzo, N. Smit, J.H. Sinisalo, J. Silander, K. Sijbrands, E.J.G. Scuteri, A. Ripatti, S. Scott, J. Schlessinger, D. Sanna, S. Salomaa, V. Saharinen, J. Sabatti, C. Ruokonen, A. Rudan, I. Rose, L.M. Roberts, R. Chasman, D.I. Rieder, M. Psaty, B.M. Pramstaller, P.P. Pichler, I. Perola, M. Penninx, B.W.J.H. Pedersen, N.L. Pattaro, C. Parker, A.N. Pare, G. Willer, C.J. Oostra, B.A. Nieminen, M.S. Nickerson, D.A. Montgomery, G.W. Meitinger, T. McPherson, R. McCarthy, M.I. McArdle, W.L. Masson, D. Martin, N.G. |
2010-08-05
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Genetic variation at the phospholipid transfer protein locus affects its activity and high-density lipoprotein size and is a novel marker of cardiovascular disease susceptibility
(Article)
Vergeer, M. Boekholdt, S.M. Hofman, A. Uitterlinden, A.G. Duijn, C.M. van Witteman, J.C.M. Jukema, J.W. Schadt, E.E. Schoot, E. van der Kastelein, J.J. Khaw, K-T. Dullaart, R.P.F. Sandhu, M.S. Tol, A. van Trip, M.D. Dallinga-Thie, G.M. Ricketts, S.L. Wareham, N.J. Brown, M.J. Faire, U.D. Leander, K. Gigante, B. Kavousi, M. |
2010-08-03
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Carotid atherosclerosis progression in familial hypercholesterolemia patients: A pooled analysis of the ASAP, ENHANCE, RADIANCE 1, and CAPTIVATE studies
(Article)
Vergeer, M. Zhou, R. Sijbrands, E.J.G. Pasternak, R.C. Gagné, C. Marais, A.D. Ballantyne, C. Isaacsohn, J.L. Stalenhoef, A.F. Kastelein, J.J. Bots, M.L. Duivenvoorden, R. Koglin, J. Akdim, F. Mitchel, Y.B. Huijgen, R. Sapre, A. Groot, E. de |
2010-07-01
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Efficacy and Safety of Mipomersen, an Antisense Inhibitor of Apolipoprotein B, in Hypercholesterolemic Subjects Receiving Stable Statin Therapy
(Article)
Akdim, F. Stroes, E.S.G. Wedel, M.K. Kastelein, J.J. Sijbrands, E.J.G. Tribble, D.L. Trip, M.D. Jukema, J.W. Flaim, J.D. Su, J. Yu, R. Baker, B.F. |
2010-04-13
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The risk of tendon xanthomas in familial hypercholesterolaemia is influenced by variation in genes of the reverse cholesterol transport pathway and the low-density lipoprotein oxidation pathway
(Article)
Oosterveer, D.M. Versmissen, J. Yazdanpanah, M. Defesche, J.C. Kastelein, J.J. Sijbrands, E.J.G. |
2010-04-01
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Two years after molecular diagnosis of familial hypercholesterolemia: Majority on cholesterol-lowering treatment but a minority reaches treatment goal
(Article)
Huijgen, R. Kindt, I. Verhoeven, S.B.J. Sijbrands, E.J.G. Vissers, M.N. Kastelein, J.J. Hutten, B.A. |
2010-02-15
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Separating the mechanism-based and off-target actions of cholesteryl ester transfer protein inhibitors with CETP gene polymorphisms
(Article)
Sofat, R. Hingorani, A. Wareham, N.J. Khaw, K-T. Kumari, M. Kivimaki, M. Marmot, M. Asselbergs, F.W. Harst, P. van der Dullaart, R.P.F. Navis, G. Veldhuisen, D.J. van Smeeth, L. Gilst, W.H. van Thompson, J.F. McCaskie, P. Palmer, C. Arca, M. Quagliarini, F. Gaudio, C. Cambien, F. Nicaud, V. Poirer, O. Humphries, S.E. Gudnason, V. Isaacs, A. Witteman, J.C.M. Tikka-Kleemola, P. Pencina, M. Vasan, R.S. D'Agostino, R.B. Ordovas, J.M. Li, T.Y. Kakko, S. Talmud, P.J. Kauma, H. Savolainen, M.J. Kesäniemi, Y.A. Sandhofer, A. Paulweber, B. Sorli, J.V. Goto, A. Yokoyama, S. Okumura, K. Horne, B.D. Cooper, J. Packard, C. Freeman, D. Ford, I. Sattar, N. McCormack, V. Lawlor, D.A. Ebrahim, S. Smith, G.D. Kastelein, J.J. Deanfield, J. Shah, T. Casas, J.P. Sandhu, M.S. Ricketts, S.L. Boekholdt, S.M. |
2010-01-01
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