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lymph nodes lymph patient macrophage antigen disease tissue expression sclerosis control arthritis cytokine peptidoglycan spleen brain antibody myelin cns-draining lymph nodes receptor study immunol blood model production proliferation response myelin-laden macrophages ra patients sample number ms patients result somatostatin adjuvant induction animal synovial presence myelin-laden protein t cells lesion sclerosis patients biozzi abh mice monkey dendritic cells c 57bl mice system pg-containing cells laman journal subtype synovial uid stimulation marmoset t-cell antigen-containing cells experiment adjuvant arthritis cns-draining level peptide method hazenberg myelin ingestion gelatinase 2/1 preparation cns antigens staining lymphoid ccr 7 chemokine analysis table leukocyte cytokine production damage sclerosis brain tissue monocyte
10 Most Recent Publications
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Myelin ingestion alters macrophage antigen-presenting function in vitro and in vivo
(Article)
Zwam, M. van Samsom, J.N. Laman, J.D. Nieuwenhuis, E.E.S. Melief, M.J. Wierenga-Wolf, A.F. Dijke, I.E. Talens, S. Meurs, M. van Voerman, J.S. Boven, L.A. |
2011-07-01
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Myelin ingestion by macrophages promotes their motility and capacity to recruit myeloid cells
(Article)
Zwam, M. van Wierenga-Wolf, A.F. Melief, M.J. Schrijver, B. Laman, J.D. Boven, L.A. |
2010-08-01
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Epstein Barr virus is not a characteristic feature in the central nervous system in established multiple sclerosis
(Article)
Peferoen, L.A.N. Lamers, F. Nierop, G.P. van Vos, W. Peferoen-Baert, R.M.B. Middeldorp, J.M. Valk, P. van der Amor, S. Lodder, L.N.R. Gerritsen, W. Huitinga, I. Melief, M.J. Giovannoni, G. Meier, U. Hintzen, R.Q. Verjans, G.M.G.M. |
2010-05-01
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A monoclonal antibody selection for immunohistochemical examination of lymphoid tissues from non-human primates
(Article)
Kap, Y.S. Meurs, M. van Driel, N. van Koopman, G. Melief, M.J. Brok, H.P.M. Laman, J.D. Hart, B. 't |
2009-12-01
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Surgical excision of CNS-draining lymph nodes reduces relapse severity in chronic-relapsing experimental autoimmune encephalomyelitis
(Article)
Zwam, M. van Huizinga, R. Laman, J.D. Heijmans, N. Meurs, M. van Wierenga-Wolf, A.F. Melief, M.J. Hintzen, R.Q. Hart, B.A.T. Amor, S. Boven, L.A. |
2009-03-01
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Brain antigens in functionally distinct antigen-presenting cell populations in cervical lymph nodes in MS and EAE
(Article)
Zwam, M. van Huizinga, R. Bechmann, I. Hintzen, R.Q. Hart, B. 't Amor, S. Laman, J.D. Boven, L.A. Melief, M.J. Wierenga-Wolf, A.F. Meurs, M. van Voerman, J.S. Biber, K.P.H. Boddeke, H.W.G.M. Höpken, U.E. Meisel, C. |
2009-03-01
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Proinflammatory bacterial peptidoglycan as a cofactor for the development of central nervous system autoimmune disease
(Article)
Visser, L. Laman, J.D. Riel, D.A.J. van Heer, H.J. de Boven, L.A. Meurs, M. van Melief, M.J. Zahringer, U. Strijp, J. van Lambrecht, B.N.M. Nieuwenhuis, E.E.S. |
2005-01-01
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Peptidoglycan from sterile human spleen induces T-cell proliferation and inflammatory mediators in rheumatoid arthritis patients and healthy subjects
(Article)
Schrijver, I.A. Melief, M.J. Markusse, H.M. Aelst, I. van Opdenakker, G. Hazenberg, M.P. Laman, J.D. |
2001-01-01
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Bacterial peptidoglycan and immune reactivity in the central nervous system in multiple sclerosis
(Article)
Schrijver, I.A. Meurs, M. van Melief, M.J. Buljevac, D. Ravid, R. Hazenberg, M.P. Laman, J.D. Ang, C.W. |
2001-01-01
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Somatostatin receptor subtype expression in cells of the rat immune system during adjuvant arthritis
(Article)
Bokum, A.M.C. ten Lichtenauer-Kaligis, E.G. Melief, M.J. Koetsveld, P.M. van Bruns, C. Hagen, P.M. van Hofland, L.J. Lamberts, S.W.J. Hazenberg, M.P. |
1999-01-01
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