Rescigno, M.

nod 2 disease crohn receptor response nod 1 protein mutation epithelial cells flammatory function bacteria domain nod proteins flammatory response paneth cells epithelial patient ligand monocyte-derived dendritic cells nod 2 mutation fl agellin macrophage dendritic expression activation immunol intracellular recognition cytokine development flammatory bowel disease binding review speci nod 2 variants flammation nod 2 mutations dendritic cells william fi ndings variant muramyl dipeptide oligomerization lippincott caspase paneth agellin wilkin nf-kb activation production toll-like nf-kb constituent infection factor monocyte pattern nucleotide tlr ligands il -8 1007f reproduction secretion toll-like receptors 2/rick protein kinase factor kappa b article nding nod 2 gene result blood monocytes mucosal level interleukin 1 beta speci fic cells kinase copyright oligomerization domain gastroenterology