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scopus: 7004733785

Bruijn, P. de

(Peter de Bruijn)


patient cancer plasma concentration study pharmacokinetic irinotecan sample paclitaxel treatment analysis sn -38 infusion metabolite -38 method course cpt -11 docetaxel tumor phase level -11 blood effect diarrhea value clearance solution toxicity table tamoxifen potassium edta plasma administration sparreboom grade lithium heparinized plasma neomycin cycle cyp 3a activity verweij sunitinib dosing exposure inhibitor verweij j disposition group oncol sn -38g pharmacol metabolism sam 486a vinorelbine netherland variability aliquots tissue microdialysi omeprazole ratio xuorouracil plasma samples agent 5- xuorouracil cremophor el parameter journal -8951 dialysis interindividual variability light / journal binding carboplatin result extraction urine fraction




10 Most Recent Publications

Long-term prospective population PK study in GIST patients - Response (Article)
Mathijssen, R.H.J. Bruijn, P. de Eechoute, K. Sparreboom, A.
2013-02-15
Quantification of tamoxifen and three of its phase-I metabolites in human plasma by liquid chromatography/triple-quadrupole mass spectrometry (Article)
Binkhorst, L. Mathijssen, R.H.J. Ghobadi Moghaddam-Helmantel, I.M. Bruijn, P. de Gelder, T. van Wiemer, E.A.C. Loos, W.J.
2011-12-15
Effect of omeprazole on the pharmacokinetics and toxicities of irinotecan in cancer patients: A prospective cross-over drug-drug interaction study (Article)
Bol, J.M. van der Loos, W.J. Jonge, M.J.A. de Meerten, E. van Konings, I.R.H.M. Lam, M.H. Bruijn, P. de Wiemer, E.A.C. Verweij, J. Mathijssen, R.H.J.
2011-04-01
Simultaneous quantification of dextromethorphan and its metabolites dextrorphan, 3-methoxymorphinan and 3-hydroxymorphinan in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry (Article)
Loos, W.J. Graan, A-J.M. de Bruijn, P. de Schaik, R.H.N. van Fessem, M.A. van Lam, M.H. Mathijssen, R.H.J. Wiemer, E.A.C.
2011-01-25
Therapeutic drug monitoring for the individualization of docetaxel dosing: A randomized pharmacokinetic study (Article)
Engels, F.K. Loos, W.J. Bol, J.M. van der Bruijn, P. de Mathijssen, R.H.J. Verweij, J. Mathot, R.A.A.
2011-01-15
Bioanalytical method for the quantification of sunitinib and its n-desethyl metabolite SU12662 in human plasma by ultra performance liquid chromatography/tandem triple-quadrupole mass spectrometry (Article)
Bruijn, P. de Sleijfer, S. Lam, M.H. Mathijssen, R.H.J. Wiemer, E.A.C. Loos, W.J.
2010-03-11
Increasing tumoral 5-fluorouracil concentrations during a 5-day continuous infusion: a microdialysis study (Article)
Konings, I.R.H.M. Sleijfer, S. Matthijsen, R.H.J. Bruijn, P. de Ghobadi Moghaddam-Helmantel, I.M. Dam, L.M. van Wiemer, E.A.C. Verweij, J. Loos, W.J.
2010-01-01
Validated bioanalytical method for the quantification of RGB-286638, a novel multi-targeted protein kinase inhibitor, in human plasma and urine by liquid chromatography/tandem triple-quadrupole mass spectrometry (Article)
Bruijn, P. de Moghaddam-Helmantel, I.M.G. Jonge, M.J.A. de Meyer, T. Lam, M.H. Verweij, J. Wiemer, E.A.C. Loos, W.J.
2009-12-05
Continuous ambulatory peritoneal dialysis: Pharmacokinetics and clinical outcome of paclitaxel and carboplatin treatment (Article)
Heijns, J.B. Burg, M.E.L. van der Gelder, T. van Fieren, M.W.J.A. Bruijn, P. de Gaast, A. van der Loos, W.J.
2008-10-01
Pitfalls of the application of microdialysis in clinical oncology: Controversial findings with docetaxel (Article)
Loos, W.J. Zamboni, W.C. Engels, F.K. Bruijn, P. de Lam, M.H. Wit, R. de Verweij, J. Wiemer, E.A.C.
2007-10-18
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