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dai: 298697998
scopus: 35587561600

Brinkman, A.

(Arend Brinkman)


protein cancer breast growth binding igfbp expression patient factor bcar 1 breast cancer receptor level sequence analysis tumor tamoxifen resistance region igf-i 130ca status serum treatment domain igfbp-l result insulin-like breast cancer cells insulin tissue zr -75-1 cells therapy residue cell lines oestrogen addition antiestrogen model bcar 1/p clone gene expression p 130cas medium bcar 1 levels tamoxifen resistance bcar 1/p protein disease proliferation study binding proteins dna synthesis -75-1 table culture figure agthoven ncor 2 hef 1 brinkman survival response fragment concentration igf binding menopausal status structure effect presence fluid tamoxifen therapy estrogen synthesis hormone dorsser stimulation function position bcar 1 gene prognostic




8 Most Recent Publications

CITED2 and NCOR2 in anti-oestrogen resistance and progression of breast cancer (Article)
Agthoven, T.L.A. van Sieuwerts, A.M. Foekens, J.A. Dorssers, L.C.J. Veldscholte, J. Meijer van Gelder, M.E. Smid, M. Brinkman, A. Dekker, A.T. den Leroy, I.M. IJcken, W.F.J. van Sleijfer, S.
2009-12-01
The substrate domain of BCAR1 is essential for anti-estrogen-resistant proliferation of human breast cancer cells (Article)
Brinkman, A. Jong, D. de Tuinman, S. Azaouagh, N. Agthoven, T.L.A. van Dorssers, L.C.J.
2009-01-01
Breast cancer oestrogen independence mediated by BCAR1 or BCAR3 genes is transmitted through mechanisms distinct from the oestrogen receptor signalling pathway or the epidermal growth factor receptor signalling pathway. (Article)
Dorssers, L.C.J. Brinkman, A. Veldscholte, J. Smid, M. Dechering, K.J. Agthoven, A.J. van
2005-01-01
The prognostic value of BCAR1 in patients with primary breast cancer. (Article)
Dorssers, L.C.J. Grebenchtchikov, N. Tienoven, D.T. van Geurts-Moespot, A. Span, P.N. Foekens, J.A. Sweep, F.C. Brinkman, A. Look, M.P. Broekhoven, S.P. van Jong, D. de Peters, H.A. Portengen, H. Meijer van Gelder, M.E. Klijn, J.G.M.
2004-09-15
Application of a newly developed ELISA for BCAR1 protein for prediction of clinical benefit of tamoxifen therapy in patients with advanced breast cancer. (Article)
Dorssers, L.C.J. Grebenchtchikov, N. Brinkman, A. Look, M.P. Klijn, J.G.M. Geurts-Moespot, A. Span, P.N. Foekens, J.A. Sweep, C.G.
2004-08-01
BCAR1, a human homologue of the adapter protein p130Cas, and antiestrogen resistance in breast cancer cells (Article)
Brinkman, A. Flier, S. van der Kok, E.M. Dorssers, L.C.J.
2000-01-01
Bcar1/p130Cas protein and primary breast cancer: prognosis and response to tamoxifen treatment (Article)
Flier, S. van der Brinkman, A. Look, M.P. Kok, E.M. Meijer van Gelder, M.E. Klijn, J.G.M. Dorssers, L.C.J. Foekens, J.A.
2000-01-01
Insulin-like growth factor binding protein-1 : isolation of the gene and characterization of the protein (Doctoral Thesis)
Brinkman, A.
1994-01-05