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receptor protein androgen binding expression activity mutation interaction study domain patient androgen receptor analysis level cancer presence glucocorticoid promoter concentration transcription prostate carrier assay result endocrinol hormone fraction residue sequence tissue polymorphism effect peptide library erasmus mc 22/23ek carriers transcriptional 22/23ek cortisol variant testosterone factor activation motif control experiment n 363s carriers isoform erythrocyte lncap table development plasmid region wild-type absence function r 1881 fxxlf steroid response subject system regulation phosphorylation difference growth cho cells n /c interaction position tif 2 downloaded membrane tumor ligand gr gene testi coactivator amount transfected figure
10 Most Recent Publications
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Functional analysis of novel androgen receptor mutations in a unique cohort of Indonesian patients with a disorder of sex development
(Article)
Elfferich, P. Juniarto, A.Z. Drop, S.L.S. Faradz, S.M.H. Brüggenwirth, H.T. Brinkmann, A.O. Dubbink, H.J. Royen, M.E. van Molier, M. Hoogerbrugge, J.W. Houtsmuller, A.B. Trapman, J. Santosa, A. Jong, F.H. de |
2009-12-01
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DNA dependent recruitment of DDX17 and other interacting proteins by the human androgen receptor
(Article)
Wong, H.Y. Demmers, J.A. Bezstarosti, K. Grootegoed, J.A. Brinkmann, A.O. |
2009-02-01
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Prediction of Progression of Non-Muscle-Invasive Bladder Cancer by WHO 1973 and 2004 Grading and by FGFR3 Mutation Status: A Prospective Study
(Article)
Burger, M. Aa, M.N.M. van der Wieland, W.F. Hofstaedter, F. Hartmann, A. Zwarthoff, E.C. Oers, J.M.M. van Brinkmann, A.O. Kwast, Th.H. van der Steyerberg, E.W. Stoehr, R. Kirkels, W.J. Denzinger, S. Wild, P.J. |
2008-10-01
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A novel mutation F826L in the human androgen receptor in partial androgen insensitivity syndrome; increased NH2-/COOH-terminal domain interaction and TIF2 co-activation
(Article)
Wong, H.Y. Hoogerbrugge, J.W. Wolffenbuttel, K.P. Trapman, J. Kleijer, W.J. Drop, S.L.S. Grootegoed, J.A. Brinkmann, A.O. Pang, K.L. Leeuwen, M. van Royen, M.E. van Molier, M. Berrevoets, C.A. Dooijes, D. Dubbink, H.J. Wijngaart, D.J. van de |
2008-09-24
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Detailed functional studies on androgen receptor mild mutations demonstrate their association with male infertility
(Article)
Zuccarello, D. Ferlin, A. Vinanzi, C. Prana, E. Garolla, A. Callewaert, L. Claessens, F. Brinkmann, A.O. Foresta, C. |
2008-04-01
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Proteomic analysis of proteins regulated by TRPS1 transcription factor in DU145 prostate cancer cells
(Article)
Chang, G.T.G. Gamble, S.C. Jhamai, M. Wait, R. Bevan, C.L. Brinkmann, A.O. |
2007-05-01
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Associations between promoter usage and alternative splicing of the glucocorticoid receptor gene
(Article)
Russcher, H. Dalm, V.A.S.H. Jong, F.H. de Brinkmann, A.O. Hofland, L.J. Lamberts, S.W.J. Koper, J.W. |
2007-02-01
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Lack of Association of the 11beta-hydroxysteroid dehydrogenase type 1 gene 83,557insA and hexose-6-phosphate dehydrogenase gene R453Q polymorphisms with body composition, adrenal androgen production, blood pressure, glucose metabolism, and dementia.
(Article)
Smit, P. Dekker, M.J.H.J. Jong, F.J. de Beld, A.W. van den Koper, J.W. Pols, H.A.P. Brinkmann, A.O. Jong, F.H. de Breteler, M.M.B. Lamberts, S.W.J. |
2007-01-01
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Two polymorphisms in the glucocorticoid receptor gene directly affect glucocorticoid-regulated gene expression.
(Article)
Russcher, H. Smit, P. Akker, E.L.T. van den Rossum, E.F.C. van Brinkmann, A.O. Jong, F.H. de Lamberts, S.W.J. Koper, J.W. |
2005-10-01
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A common polymorphism in the CYP3A7 gene is associated with a nearly 50% reduction in serum dehydroepiandrosterone sulfate levels.
(Article)
Smit, P. Schaik, R.H.N. van Werf, M.J. van der Beld, A.W. van den Koper, J.W. Lindemans, J. Pols, H.A.P. Brinkmann, A.O. Jong, F.H. de Lamberts, S.W.J. |
2005-09-01
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