Chrousos, G.P.

variant receptor type gr glucocorticoid transcription promoter repression expression transcriptional plasmid library erasmus mc binding gr variants glucocorticoid resistance protein glucocorticoid receptor mutation concentration v 729i variant ligand activation table resistance capacity i 559n hgr variants r 23k ligand concentrations change activity factor position domain n 363s variants reporter hormone element regulation erasmu level potency kind gift transfection transcriptional activation function point mutations point 641v variant response downloaded cortisol library january endocrinol receptor variant receptor variants transcriptional repression gene regulation error bars acid alterations collagenase promoter interaction mmtv promoter residue type levels fragment presence prl 3-tk collagenase lambert netherland system vector shock assay p 65 protein j clin signal transduction pathways cotransfected molecule